Prof. Jürgen Popp.
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Biophotonics

Prof. Jürgen Popp.
Image: Jan-Peter Kasper (University of Jena)
Prof. Dr. Jürgen Popp Image: Leibniz-IPHT.

Prof. Dr. Jürgen POPP

Email: juergen.popp@uni-jena.de
Phone: +49 3641-9-48320

Research areas

The core of the research activities focuses on researching, developing and implementing innovative optical/photonic methods and tools for multiscale spectroscopy and multimodal imaging together with particle- and chip-based molecular point-of-care concepts for analytics, diagnostics and therapy in the fields of medicine, life and environmental sciences, quality and process analytics as well as pharmacy. The implementation of novel fiber concepts for spectroscopy and imaging as well as fiber-assisted sensor technology and the use of surface-enhanced detection techniques to increase the sensitivity of spectroscopic methods complete the research profile. In general, the research pursues the goal of covering the entire analysis measurement chain, whereby sample preparation methods that can be used locally and independently of the laboratory are investigated and implemented in the entire workflow. Statistical, chemometric and image-evaluating methods as well as machine learning are researched and used to evaluate the data obtained.

Addressed Application Fields

  • Microbial photonic diagnostics (pathogen / host / companion)
  • Infection diagnostics
  • Spectral histopathology (molecular spectroscopy, high-resolution and hyperspectral imaging)
  • Medical, environmental, pharmaceutical, food and process analytics

Teaching fields

Prof. Popp gives courses in:

  • fundamentals of physical chemistry
  • innovative spectroscopy and imaging approaches for biophotonics
  • Raman spectroscopy for biomedical diagnostics

Research methods

The laboratories led by Prof. Popp offer a wide range of laser (micro)spectroscopic methods, at which almost the complete value chain of Raman-based approaches is available:

  • Raman (micro)spectroscopy with excitation wavelengths ranging from the UV into the NIR
  • Resonance Raman (micro)spectroscopy
  • Surface enhanced Raman spectroscopy (SERS)
  • IR absorption/ ATR-IR spectroscopy
  • Coherent Raman imaging (CARS, SRS)
  • Second harmonic generation (SHG) microscopy
  • Multi-photon excited fluorescence microscopy
  • Fluorescence Life-Time Imaging Microscopy (FLIM)
  • UV/ Vis absorption spectroscopy
  • Steady state fluorescence spectroscopy
  • Optical coherence tomography (OCT)
  • Hyperspectral Imaging

link to the Biophotonics Group

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