INSTITUTE OF APPLIED PHYSICS - Microbiology & Molecular Biology
URL: http://www.iap.uni-jena.de/brakhage.print
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Microbiology & Molecular Biology

Research areas

Our research aims to elucidate the pathobiology of A. fumigatus, including the areas of physiology/biochemistry, signal transduction, improvement of genetic techniques, genomics, proteomics, transcriptomics, glycoconjugates, pathogen/host interaction and an animal model. Fungi produce numerous of secondary metabolites. Some of these compounds are used as antibiotics or as immunosuppressants. Besides the identification and characterisation of novel microorganisms producing secondary metabolites, recent research has aimed at elucidating the molecular regulation of the biosyntheses of secondary metabolites. Prof. Brakhage's research focuses on all aspects of the pathobiology of Aspergillus fumigatus and on the molecular biology/ biotechnology of fungal secondary metabolites and related microbial communication, including:

Teaching fields

Prof. Brakhage's teaching is devoted to the early involvement of young scientists in research, as well as to the education of postgraduates. He gives courses in:

Research methods

The laboratory led by Prof. Brakhage offers methods for the characterization of immune effector cells, the molecular biology of fungi, biochemistry and biotechnology:

>> link to the Microbiology & Molecular Biology Group