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FIBER SPECTROSCOPIC SENSING

Research areas

Torsten Frosch's research interests address the development of highly sensitive and miniaturized Rama spectroscopic sensing techniques for interdisciplinary research in the areas of environmental, pharmaceutical and biomedical analysis. Research thrusts include:

  • novel hollow-core fibers for low-loss light guidance in the visible and ultraviolet spectral range
  • development of cavity enhanced and fiber enhanced Raman spectroscopy (CERS and FERS)
  • ultrasensitive FERS analysis of pharmaceutical drugs and biomolecules
  • CERS multi-gas sensing for environmental monitoring and investigation of biogeochemical processes
  • chemical imaging of biological cells and pharmaceuticals
  • Raman difference spectroscopy for investigation of drug-target interactions

The research interests of the group are thus concerned with innovative, miniaturized, optical fibers and cavities for chemical selective and highly sensitive spectroscopic analysis in environmental, pharmaceutical and biomedical areas. In particular, the new techniques Cavity Enhanced and Fiber Enhanced Raman Spectroscopy (CERS and FERS) provide unique capabilities for chemo- and bioanalysis such as applicability in hydrous/biological environment as well as label-free, non-destructive, and simultaneous analysis and quantification of several analytes. Raman sensing in hollow-core optical fibers takes advantage of the efficient light-analyte-interaction and can be exploited for trace analysis of minimal sample amounts. One of our special interests is the spectral extension of low loss light guidance in hollow-core fibers. The development of novel double antiresonant hollow-core fibers provides light guidance with Gaussian-type mode quality in transmission windows spanning from the near infrared to the deep ultraviolet. These novel fibers are extremely promising for our research in biospectroscopy.

Another research focus of our group is spectroscopic gas sensing with strong links to the CRC "AquaDiva". Various interdisciplinary research projects are concerned with environmental analysis and eco-physiological studies. Enhanced Raman spectroscopy is also applied for the analysis of gaseous and volatile disease markers in breath for non-invasive early stage disease diagnosis.

Frosch_research_contribution02

Novel double antiresonant hollow-core fibers for biosensing in the deep ultraviolet spectral range.

Teaching fields

Dr. Frosch is actively involved in teaching physical chemistry courses for chemistry and pharmacy students. He contributes to the education and support of doctoral candidates with lectures in analytical methods at the International Max Planck Research School for Global Biogeochemical Cycles. His teaching is devoted to the early involvement of students and young scientists in state-of-the-art research.

Research methods

The laboratories led by Torsten Frosch, and the infrastructure at the Leibniz Institute of Photonic Technology, offer a wide range of spectroscopic methods, different lasers and Raman spectrometers as well as a fiber drawing tower facility for the development of novel hollow fibers. Several miniaturized and home-built Raman sensors are developed for interdisciplinary research and are applied for onsite analysis.

>> link to the Fiber Spectroscopic Sensing Group

 

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